Platelet-dependent thrombin generation after in vitro fibrinolytic treatment.

@article{Aronson1992PlateletdependentTG,
  title={Platelet-dependent thrombin generation after in vitro fibrinolytic treatment.},
  author={David L Aronson and Peter W. Chang and Craig Kessler},
  journal={Circulation},
  year={1992},
  volume={85 5},
  pages={1706-12}
}
BACKGROUND Fibrinolytic therapy is associated with frequent rethrombosis. There is evidence of both increased coagulation and platelet activation. METHODS AND RESULTS Platelet-rich plasma (PRP) or washed platelets were incubated with the fibrinolytic agents urokinase, recombinant tissue-type plasminogen activator (rt-PA), or plasmin at concentrations… CONTINUE READING