Platelet-associated immunoglobulin G in childhood idiopathic thrombocytopenic purpura.

@article{Lightsey1979PlateletassociatedIG,
  title={Platelet-associated immunoglobulin G in childhood idiopathic thrombocytopenic purpura.},
  author={Alton L Lightsey and Harold M Koenig and Robert McMillan and Jeannie R Stone},
  journal={The Journal of pediatrics},
  year={1979},
  volume={94 2},
  pages={
          201-4
        }
}
Childhood ITP is an acquired hemorrhagic disorder with a heterogeneous clinical course. We measured PAIgG levels in 20 children with ITP (7 acute, 13 chronic). Both groups had significantly greater PAIgG values than age-matched normal subjects and thrombocytopenic controls (P less than 0.001). In addition, PAIgG values in chronic ITP were significantly lower than those in acute ITP (P less than 0.003). Serial PAIgG values were obtained in some patients; most returned to normal in association… CONTINUE READING