Platelet-associated immunoglobulin (antiplatelet antibody) in canine Rocky Mountain spotted fever and ehrlichiosis.

@article{Grindem1999PlateletassociatedI,
  title={Platelet-associated immunoglobulin (antiplatelet antibody) in canine Rocky Mountain spotted fever and ehrlichiosis.},
  author={Carol B. Grindem and Edward B Breitschwerdt and Paula C. Perkins and L D Cullins and T J Thomas and Barbara C. Hegarty},
  journal={Journal of the American Animal Hospital Association},
  year={1999},
  volume={35 1},
  pages={56-61}
}
Antiplatelet antibodies were detected in the sera of dogs with naturally occurring and experimentally induced Rickettsia rickettsii and Ehrlichia canis infections. This is the first known report documenting elevated platelet-associated immunoglobulin (PAIg) titers in Rocky Mountain spotted fever (RMSF) infections. In the naturally occurring RMSF infections and ehrlichiosis, the antibodies persisted for weeks or months, even when the platelet counts had normalized. Results of this study indicate… CONTINUE READING
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