Platelet antigens and antibody detection.

  title={Platelet antigens and antibody detection.},
  author={Paul Metcalfe},
  journal={Vox sanguinis},
  volume={87 Suppl1},
Platelets are anucleate blood cells, which play an important part in haemostasis and maintenance of the integrity of blood-vessel endothelium. Interaction of platelet glycoproteins (GPs) with extracellular matrix proteins is critical to this function. The original impetus for investigating the alloantigens found on the GPs of the platelet membrane came from clinical observations of pathological conditions involving antibodies against platelet-specific antigens. Since then, dramatic progress has… CONTINUE READING


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