Platelet and leukocyte activation in salvaged blood and the effect of its reinfusion on the circulating blood.

@article{Jong2007PlateletAL,
  title={Platelet and leukocyte activation in salvaged blood and the effect of its reinfusion on the circulating blood.},
  author={Marion de Jong and Michael J Ray and Scott Alan Crawford and Sarah Lilian Whitehouse and Ross Crawford},
  journal={Clinical orthopaedics and related research},
  year={2007},
  volume={456},
  pages={238-42}
}
Postoperative wound drainage reinfusion reduces the frequency of homologous blood transfusion. The salvaged blood is depleted of coagulation factors but may contain platelets and leukocytes which are activated, and therefore potentially procoagulant. We ascertained the degree of activation of platelets and leukocytes in salvaged blood and asked whether their infusion produced any measurable effect on patients' coagulation system. We prospectively randomized 24 patients who had total knee… CONTINUE READING