Platelet adhesion and arteriolar dilation in the photothrombosis: observation with the rat closed cranial and spinal windows.

@article{Ishikawa2002PlateletAA,
  title={Platelet adhesion and arteriolar dilation in the photothrombosis: observation with the rat closed cranial and spinal windows.},
  author={Mami Ishikawa and Eiichi Sekizuka and Chikara Oshio and Shuzo Sato and Noriyuki Yamaguchi and Satoshi Terao and Kosuke Tsukada and Haruyuki Minamitani and Takeshi Kawase},
  journal={Journal of the neurological sciences},
  year={2002},
  volume={194 1},
  pages={59-69}
}
The mechanism of cerebral infarction, in which thrombus formation and platelet-endothelium interaction play an important part, have not yet been clearly elucidated in vivo. The aim of this study was to observe rolling and adherent platelets and to analyze adherent leukocytes and vessel diameter change in vivo using a photothrombotic vessel occlusion model.A photothrombosis, which is mediated by free radicals, was induced in male Wistar rats in the presence of a photosensitizing dye (Photofrin… CONTINUE READING
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