Platelet activation patterns in platelet size sub-populations: differential responses to aspirin in vitro

@article{Mangalpally2010PlateletAP,
  title={Platelet activation patterns in platelet size sub-populations: differential responses to aspirin in vitro},
  author={Kiran Kumar R. Mangalpally and Alan Siqueiros-Garcia and Muthiah Vaduganathan and Jing-fei Dong and Neal S. Kleiman and Sasidhar Guthikonda},
  journal={Journal of Thrombosis and Thrombolysis},
  year={2010},
  volume={30},
  pages={251-262}
}
Circulating platelets are heterogeneous in size and structure. Whether this translates into differences in platelet function and efficacy of antiplatelet therapy is unclear. Hence, we decided to investigate the activation patterns among different platelet populations differentiated by size, and to compare the inhibitory effects of aspirin in these… CONTINUE READING