Platelet activation on hemodialysis: influence of dialysis membranes.

  title={Platelet activation on hemodialysis: influence of dialysis membranes.},
  author={Aleix Cases and Juan Carlos Reverter and Gin{\'e}s Escolar and Cristina Sanz and Jos{\'e} L{\'o}pez-Pedret and Lu{\'i}s Revert and Antonio Ordinas},
  journal={Kidney international. Supplement},
During hemodialysis, platelets are activated and release alpha-granule-specific proteins. GMP-140 is a glycoprotein stored in the alpha-granules of platelets, which is selectively expressed on the plasma membrane of activated platelets. Using a specific monoclonal antibody against this protein (CD 62), we have evaluated the influence of different dialysis membranes on hemodialysis-induced platelet activation in vivo by flow cytometry in nine patients with end-stage renal disease on maintenance… CONTINUE READING
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