Platelet activation during coronary angioplasty in humans.

  title={Platelet activation during coronary angioplasty in humans.},
  author={Christine Gasperetti and Steven L Gonias and Lawrence W. Gimple and Eric R. Powers},
  volume={88 6},
BACKGROUND Previous studies have indicated that balloon angioplasty is associated with local platelet activation. In addition, different contrast media have different effects on thrombus formation during angioplasty in humans. We hypothesized that coronary angioplasty in humans is associated with activation of platelets to specific platelet agonists and that this activation may be differently modified by different angiographic contrast agents. METHODS AND RESULTS We studied 25 patients… CONTINUE READING