Platelet activation, coagulation and angiogenesis in breast and prostate carcinoma.

@article{Caine2004PlateletAC,
  title={Platelet activation, coagulation and angiogenesis in breast and prostate carcinoma.},
  author={Graham J Caine and Gregory Y. H. Lip and Paul S Stonelake and Peter A. Ryan and Andrew D. Blann},
  journal={Thrombosis and haemostasis},
  year={2004},
  volume={92 1},
  pages={185-90}
}
In health, haemostasis and angiogenesis are tightly regulated processes, but may become deregulated in cancer. Recent evidence suggests that platelet activation may link these processes as platelets can release angiogenic factors such as vascular endothelial growth factor (VEGF). Furthermore, inflammation has also been implicated in regulating both coagulation and angiogenesis, possibly by activating platelets directly and increasing, for example, plasma fibrinogen. We hypothesized… CONTINUE READING