Platelet-activating factor acetylhydrolase is mainly associated with electronegative low-density lipoprotein subfraction.

@article{Bentez2003PlateletactivatingFA,
  title={Platelet-activating factor acetylhydrolase is mainly associated with electronegative low-density lipoprotein subfraction.},
  author={Sonia Elizabeth Ben{\'i}tez and Jos{\'e} Luis S{\'a}nchez-Quesada and Vicent J. Ribas and Oscar Jorba and Francisco Blanco-Vaca and Francesc Gonz{\'a}lez-Sastre and Jordi Ord{\'o}{\~n}ez-Llanos},
  journal={Circulation},
  year={2003},
  volume={108 1},
  pages={92-6}
}
BACKGROUND Electronegative LDL [LDL(-)], a modified subfraction of LDL present in plasma, induces the release of interleukin-8 and monocyte chemotactic protein-1 from cultured endothelial cells. METHODS AND RESULTS We demonstrate that platelet-activating factor acetylhydrolase (PAF-AH) is mainly associated with LDL(-). LDL(-) had 5-fold higher PAF-AH activity than the nonelectronegative LDL subfraction [LDL(+)] in both normolipemic and familial hypercholesterolemic subjects. Western blot… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 31 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 30 references

Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase: a potential new risk factor for coronary heart disease

  • MJ Caslake, CJ Packard, KE Suckling
  • Atherosclerosis
  • 2000

Similar Papers

Loading similar papers…