Platelet-activating factor--a powerful lipid autacoid possibly involved in microangiopathy.

@article{Bussolino1986PlateletactivatingFP,
  title={Platelet-activating factor--a powerful lipid autacoid possibly involved in microangiopathy.},
  author={Federico Bussolino and P M Biffignandi and Paolo Arese},
  journal={Acta haematologica},
  year={1986},
  volume={75 3},
  pages={129-40}
}
Microvascular injury includes diffuse endothelial and periendothelial damage and increased leukocyte/platelet-endothelium interactions including cell adhesion and liberation of powerful autacoids, growth and coagulation factors, all capable of causing vessel wall injury. Platelet-activating factor (PAF) is an ether-lipid mediator of inflammation, produced… CONTINUE READING