Platelet-activating factor: receptors and signal transduction.

  title={Platelet-activating factor: receptors and signal transduction.},
  author={W Chao and M S Olson},
  journal={The Biochemical journal},
  volume={292 ( Pt 3)},
  • W Chao, M S Olson
  • Published 1993 in The Biochemical journal
During the past two decades, studies describing the chemistry and biology of PAF have been extensive. This potent phosphoacylglycerol exhibits a wide variety of physiological and pathophysiological effects in various cells and tissues. PAF acts, through specific receptors and a variety of signal transduction systems, to elicit diverse biochemical responses. Several important future directions can be enumerated for the characterization of PAF receptors and their attendant signalling mechanisms… CONTINUE READING