Platelet-activating factor, histamine, and tryptase levels in human anaphylaxis.

  title={Platelet-activating factor, histamine, and tryptase levels in human anaphylaxis.},
  author={Peter Vadas and Boris Perelman and Gary M. Liss},
  journal={The Journal of allergy and clinical immunology},
  volume={131 1},
BACKGROUND Platelet-activating factor (PAF) is an important mediator and correlates with anaphylaxis severity. How well PAF correlates with severity relative to histamine or tryptase is not known. OBJECTIVE To analyze the levels of PAF, histamine, and tryptase as a function of severity in patients with acute allergic reactions. METHODS PAF, histamine, and tryptase levels were measured in blood samples collected from 23 healthy volunteers and from 41 patients during acute allergic reactions… CONTINUE READING
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