Platelet Transfusions in Infants with Necrotizing Enterocolitis Do Not Lower Mortality but May Increase Morbidity

@article{Kenton2005PlateletTI,
  title={Platelet Transfusions in Infants with Necrotizing Enterocolitis Do Not Lower Mortality but May Increase Morbidity},
  author={Alexander B Kenton and Suzanne E. Hegemier and Elliot O'Brian Smith and Donough J O'donovan and Mary L. Brandt and Darrell Cass and Michael A. Helmrath and Kimberly K Washburn and Elizabeth K. Weihe and Caraciolo J. Fernandes},
  journal={Journal of Perinatology},
  year={2005},
  volume={25},
  pages={173-177}
}
OBJECTIVE:Necrotizing enterocolitis (NEC), a serious multisystemic inflammatory disease most commonly seen in premature neonates, is often associated with thrombocytopenia. Infants with severe forms of NEC commonly have platelet counts of less than 50,000/mm3, occasionally less than 10,000/mm3. Despite an absence of data to support the practice, platelet transfusions are commonly used to maintain a certain arbitrary platelet count in an effort to prevent bleeding. As platelet transfusions… CONTINUE READING