Platelet-Rich Gel Supernatants Stimulate the Release of Anti-Inflammatory Proteins on Culture Media of Normal Equine Synovial Membrane Explants

@article{Ros2015PlateletRichGS,
  title={Platelet-Rich Gel Supernatants Stimulate the Release of Anti-Inflammatory Proteins on Culture Media of Normal Equine Synovial Membrane Explants},
  author={D. L. R{\'i}os and C. L{\'o}pez and J. Carmona},
  journal={Veterinary Medicine International},
  year={2015},
  volume={2015}
}
  • D. L. Ríos, C. López, J. Carmona
  • Published 2015
  • Chemistry, Medicine
  • Veterinary Medicine International
    • The aims were as follows: (1) to evaluate the effects at 48 and 96 h of two concentrations (25 and 50%) of leukocyte and platelet-rich gel (L-PRG) and pure PRG (P-PRG) supernatants on the production/degradation in normal equine synovial membrane explants (SME) of platelet derived growth factor isoform BB, transforming growth factor beta-1, tumor necrosis factor alpha, interleukin (IL-) 4 (IL-4), IL-1 receptor antagonist (IL-1ra), and hyaluronan (HA) synthesis and (2) to correlate these… CONTINUE READING
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    References

    SHOWING 1-10 OF 42 REFERENCES
    Synovial fluid growth factor and cytokine concentrations after intra-articular injection of a platelet-rich product in horses.
    • 40
    • PDF
    Increasing Platelet Concentrations in Leukocyte-Reduced Platelet-Rich Plasma Decrease Collagen Gene Synthesis in Tendons
    • 125
    • PDF
    The Anti-inflammatory and Matrix Restorative Mechanisms of Platelet-Rich Plasma in Osteoarthritis
    • 200
    • PDF
    Effects of Platelet-Rich Plasma Composition on Anabolic and Catabolic Activities in Equine Cartilage and Meniscal Explants
    • 37
    • Highly Influential
    Effects of the breed, sex and age on cellular content and growth factor release from equine pure-platelet rich plasma and pure-platelet rich gel
    • 60
    • PDF
    Cytokine profile of autologous conditioned serum for treatment of osteoarthritis, in vitro effects on cartilage metabolism and intra-articular levels after injection
    • 83
    Cytokine and chemokine gene expression of IL-1beta stimulated equine articular chondrocytes.
    • 50
    Autologous conditioned serum: the comparative cytokine profiles of two commercial methods (IRAP and IRAP II) using equine blood.
    • 66
    • PDF
    Cytokine and catabolic enzyme expression in synovium, synovial fluid and articular cartilage of naturally osteoarthritic equine carpi.
    • 83
    Nucleotide structure of equine platelet-derived growth factor-A and -B and expression in horses with induced acute tendinitis.
    • 37