Platelet GABA-transaminase in epileptic children: influence of epilepsy and anticonvulsants.

@article{Arteaga1993PlateletGI,
  title={Platelet GABA-transaminase in epileptic children: influence of epilepsy and anticonvulsants.},
  author={Rosa Mar{\'i}a Arteaga and Jos{\'e} Luis Herranz and Juan Antonio Armijo},
  journal={Epilepsy research},
  year={1993},
  volume={14 1},
  pages={73-85}
}
The relationship between platelet GABA-transaminase (GABA-T) activity and either epilepsy or its treatment has been studied in 281 epileptic children: 55 were newly diagnosed untreated patients and 226 were chronically receiving anticonvulsants (154 in monotherapy and 72 in polytherapy). Results were compared with those from 48 control children. Untreated children had a GABA-T activity of 9.1 +/- 3.7 pmol/min/mg protein, lower than the control group (10.6 +/- 3.8 pmol/min/mg, P < 0.05), whereas… CONTINUE READING
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