Platelet-Derived Growth Factors-BB and Fibroblast Growth Factors-Base Induced Proliferation of Schwann Cells in a 3D Environment

@article{Jiang2012PlateletDerivedGF,
  title={Platelet-Derived Growth Factors-BB and Fibroblast Growth Factors-Base Induced Proliferation of Schwann Cells in a 3D Environment},
  author={Huajun Jiang and Wei Qu and Yuancheng Li and Weiliang Zhong and Weiguo Zhang},
  journal={Neurochemical Research},
  year={2012},
  volume={38},
  pages={346-355}
}
The proliferation of neonatal Schwann cells (SCs) in response to mitogenic agents has been well analyzed in vitro (mono-layer-culture method, 2D environment), but not in vivo (3D environment). To assess the mitogenic effect of platelet-derived growth factors-BB (PDGF-BB), Fibroblast Growth Factors-base (bFGF), and their combinations for SCs in collagen gel (three-dimensional, 3D environment), we have developed an integrated microfluidic device on which can reproducibly measure the proliferation… CONTINUE READING
BETA

References

Publications referenced by this paper.
SHOWING 1-10 OF 37 REFERENCES

Directional control of cell motility through focal adhesion positioning and spatial control of Rac activation.

  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2008
VIEW 1 EXCERPT

Similar Papers

Loading similar papers…