Platelet Adhesion to Native Type I Collagen Fibrils ROLE OF GPVI IN DIVALENT CATION-DEPENDENT AND -INDEPENDENT ADHESION AND THROMBOXANE

Abstract

Three glycoproteins (GPs), namely GPIa-IIa, GPVI, and GPIV, have been recently implicated in plateletcollagen adhesive interactions. We have employed antibodies to these GPs to investigate further their role in platelet adhesion to immobilized monomeric and polymeric fibrillar collagen under static conditions in the presence and the absence of Mg. In the… (More)

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