Platelet-, leucocyte- and red cell-derived microparticles in stored whole blood, with and without leucofiltration, with and without ionising radiation.

@article{Saito2018PlateletLA,
  title={Platelet-, leucocyte- and red cell-derived microparticles in stored whole blood, with and without leucofiltration, with and without ionising radiation.},
  author={Shunnichi Saito and Kenneth Eric Nollet and Alain Mayindu Ngoma and Takako Ono and H Ohto},
  journal={Blood transfusion = Trasfusione del sangue},
  year={2018},
  volume={16 2},
  pages={145-153}
}
BACKGROUND Storage lesion, including microparticle formation, has been partially characterised in whole blood, but not in all combinations of pre-storage leucofiltration and/or irradiation. MATERIALS AND METHODS Single-donor whole blood products were processed into four subunits: with and without leucofiltration, with and without X-irradiation (25 Gy). Platelet-, leucocyte-, and erythrocyte-derived microparticles and free haemoglobin were measured periodically throughout 42 days of storage… CONTINUE READING