Plasticity of perisynaptic astroglia during synaptogenesis in the mature rat hippocampus

@article{Witcher2007PlasticityOP,
  title={Plasticity of perisynaptic astroglia during synaptogenesis in the mature rat hippocampus},
  author={Mark R. Witcher and Sergei A Kirov and Kristen M. Harris},
  journal={Glia},
  year={2007},
  volume={55}
}
Astroglia are integral components of synapse formation and maturation during development. Less is known about how astroglia might influence synaptogenesis in the mature brain. Preparation of mature hippocampal slices results in synapse loss followed by recuperative synaptogenesis during subsequent maintenance in vitro. Hence, this model system was used to discern whether perisynaptic astroglial processes are similarly plastic, associating more or less with recently formed synapses in mature… Expand
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