Plasticity of motor network and function in the absence of corticospinal projection

  title={Plasticity of motor network and function in the absence of corticospinal projection},
  author={Qi Han and Changshu Cao and Yuetong Ding and Kwok-fai So and Wutian Wu and Yibo Qu and Libing Zhou},
  journal={Experimental Neurology},
Despite the obvious clinical interest, our understanding of how developmental mechanisms are redeployed during degeneration and regeneration after brain and spinal cord injuries remains quite rudimentary. In animal models of spinal cord injury, although spontaneous regeneration of descending axons is limited, compensation by intact corticospinal axons, descending tracts from the brainstem, and local intrinsic spinal networks all contribute to the recovery of motor function. Here, we… CONTINUE READING
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