Plasticity, niches, and the use of stem cells.

  title={Plasticity, niches, and the use of stem cells.},
  author={Robert Y. L. Tsai and Raja Kittappa and R D G Mckay},
  journal={Developmental cell},
  volume={2 6},
Stem cells possess the ability to self-renew and generate multiple cell types of the tissues in which they reside. Several studies have reported transdifferentiation events between different somatic stem cells. These properties have created tremendous excitement about the prospect of using stem cells from easily accessible sources for tissue engineering. However, recently, the plasticity of stem cells has met with several strong challenges. In this meeting review, we will discuss issues… CONTINUE READING

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