Plastic Heterogeneity of Innate Lymphoid Cells in Cancer.

  title={Plastic Heterogeneity of Innate Lymphoid Cells in Cancer.},
  author={Marek Wagner and Kazuyo Moro and Shigeo Koyasu},
  journal={Trends in cancer},
  volume={3 5},
Innate lymphoid cells (ILCs) fulfill important protective and reparative functions, and have thus been implicated in the maintenance of tissue homeostasis. Dysregulation of their activation is associated with several autoimmune and inflammatory diseases. The current literature on the role of ILCs in cancer is limited and our knowledge is therefore incomplete. Indeed, ILCs have been separately associated with tumor-promoting as well as tumor-suppressing activities, raising the need to understand… CONTINUE READING
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