Plasmodium vivax: isotopic, PicoGreen, and microscopic assays for measuring chloroquine sensitivity in fresh and cryopreserved isolates.

@article{Kosaisavee2006PlasmodiumVI,
  title={Plasmodium vivax: isotopic, PicoGreen, and microscopic assays for measuring chloroquine sensitivity in fresh and cryopreserved isolates.},
  author={Varakorn Kosaisavee and Rossarin Suwanarusk and François H Nosten and Dennis E. Kyle and Marion Barrends and James David Jones and Ric N Price and Bruce L. Russell and Usa Lek-Uthai},
  journal={Experimental parasitology},
  year={2006},
  volume={114 1},
  pages={
          34-9
        }
}
In vitro susceptibility tests provide information on the intrinsic response of Plasmodium vivax to antimalarials, free from confounding factors such as host immunity or relapse. This study examined the utility of radioisotope and PicoGreen assays as alternatives to the traditional microscopic examination for assessing response of P. vivax to antimalarial drugs. There was no significant difference in the mean chloroquine IC(50) of P. vivax (n=40) as determined by the microscopic (33.4 ng/ml… CONTINUE READING
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