Plasmodium falciparum sporozoite immunization protects against Plasmodium berghei sporozoite infection.

@article{Sina1993PlasmodiumFS,
  title={Plasmodium falciparum sporozoite immunization protects against Plasmodium berghei sporozoite infection.},
  author={Barbara J. Sina and Virg{\'i}lio Est{\'o}lio do Ros{\'a}rio and G R Woollett and Kiran Sakhuja and Michael R Hollingdale},
  journal={Experimental parasitology},
  year={1993},
  volume={77 2},
  pages={129-35}
}
Irradiated sporozoites are generally thought to elicit protective immune responses that are parasite stage and species specific. But immunization with Plasmodium falciparum sporozoites delivered by the bite of infected mosquitoes protects an average of 60% mice from Plasmodium berghei sporozoite infection. Protection appears to be specific as P. falciparum sporozoite-immunized mice protected against P. berghei remain susceptible to Plasmodium yoelii sporozoite infection. Passively transferred… CONTINUE READING

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