Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate

@inproceedings{Counihan2017PlasmodiumFP,
  title={Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate},
  author={Natalie A Counihan and Scott A. Chisholm and Hayley E. Bullen and Anubhav Srivastava and Paul Robert Sanders and Thorey K Jonsdottir and Greta E. Weiss and Sreejoyee Ghosh and Brendan Crabb and Darren John Creek and Paul R Gilson and Tania F de Koning-Ward},
  booktitle={eLife},
  year={2017}
}
Plasmodium falciparum parasites, the causative agents of malaria, modify their host erythrocyte to render them permeable to supplementary nutrient uptake from the plasma and for removal of toxic waste. Here we investigate the contribution of the rhoptry protein RhopH2, in the formation of new permeability pathways (NPPs) in Plasmodium-infected erythrocytes. We show RhopH2 interacts with RhopH1, RhopH3, the erythrocyte cytoskeleton and exported proteins involved in host cell remodeling… CONTINUE READING

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