Plasmodium falciparum XPD translocates in 5′ to 3′ direction, is expressed throughout the blood stages, and interacts with p44

@article{Tajedin2015PlasmodiumFX,
  title={Plasmodium falciparum XPD translocates in 5′ to 3′ direction, is expressed throughout the blood stages, and interacts with p44},
  author={Leila Tajedin and Mohammed Tarique and R. Tuteja},
  journal={Protoplasma},
  year={2015},
  volume={252},
  pages={1487-1504}
}
XPD helicase, a TFIIH subunit, is essential for several processes including transcription, NER, cell cycle regulation, and apoptosis in eukaryotes. Another component of TFIIH, namely p44, is among the well-known interacting partners of XPD and is vital in regulating the helicase activities of latter. However, none of the above mentioned proteins have been functionally characterized in Plasmodium falciparum. Consequently, in this study, we performed detailed studies on XPD and its interacting… CONTINUE READING