Plasmodium falciparum Malaria: reduction of endothelial cell apoptosis in vitro.

@article{Hemmer2005PlasmodiumFM,
  title={Plasmodium falciparum Malaria: reduction of endothelial cell apoptosis in vitro.},
  author={Christoph Josef Hemmer and Hans Anton Lehr and Kathi Westphal and Marcus Unverricht and Manja Kratzius and Emil C Reisinger},
  journal={Infection and immunity},
  year={2005},
  volume={73 3},
  pages={1764-70}
}
Organ failure in Plasmodium falciparum malaria is associated with neutrophil activation and endothelial damage. This study investigates whether neutrophil-induced endothelial damage involves apoptosis and whether it can be prevented by neutralization of neutrophil secretory products. Endothelial cells from human umbilical veins were coincubated with neutrophils from healthy donors and with sera from eight patients with P. falciparum malaria, three patients with P. vivax malaria, and three… CONTINUE READING

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