Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes

Abstract

The causative agent of malaria, Plasmodium, replicates inside a membrane-bound parasitophorous vacuole (PV), which shields this intracellular parasite from the cytosol of the host cell 1 . One common threat for intracellular pathogens is the homeostatic process of autophagy, through which cells capture unwanted intracellular material for lysosomal… (More)
DOI: 10.1038/s41564-017-0054-x

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