Plasminogen binds specifically to alpha-enolase on rat neuronal plasma membrane.

@article{Nakajima1994PlasminogenBS,
  title={Plasminogen binds specifically to alpha-enolase on rat neuronal plasma membrane.},
  author={Kazuyuki Nakajima and Makoto Hamanoue and Naoya Takemoto and Taka-aki Hattori and Kanefusa Kato and Shinichi Kohsaka},
  journal={Journal of neurochemistry},
  year={1994},
  volume={63 6},
  pages={2048-57}
}
Plasminogen (PGn) that we identified in microglial-conditioned medium has a neurotrophic factor-like effect on cultured neurons. We have also shown that PGn binds specifically to a protein with a molecular mass of 45 kDa in the neuronal plasma membrane. As a candidate PGn receptor-like molecule on the neuronal surface, this 45-kDa protein was purified from the plasma membrane of embryonic rat brain. Amino acid sequence analysis of polypeptides derived from the cleavage of the protein with… CONTINUE READING