Plasminogen activator system in human breast cancer.

  title={Plasminogen activator system in human breast cancer.},
  author={Katsuhiko Sumiyoshi and Koji Serizawa and Tetsumei Urano and Yasunobu Takada and Akikazu Takada and S. El Baba},
  journal={International journal of cancer},
  volume={50 3},
We measured antigen levels of 2 kinds of plasminogen activator, tissue-type plasminogen activator (t-PA) and urokinase-type plasminogen activator (UK), as well as those of their primary inhibitors, type-I plasminogen activator inhibitor (PAI-1) and type-2 plasminogen activator inhibitor (PAI-2), in tissue extracts from benign and malignant breast tumors. Tumor tissue samples from 40 fibroadenomas and 40 breast cancers were examined. t-PA antigen levels were the same in the 2 groups. Malignant… CONTINUE READING


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