Plasminogen activator system and vascular disease.

@article{Nicholl2006PlasminogenAS,
  title={Plasminogen activator system and vascular disease.},
  author={Suzanne M. Nicholl and Elisa Roztocil and Mark G Davies},
  journal={Current vascular pharmacology},
  year={2006},
  volume={4 2},
  pages={
          101-16
        }
}
Vascular diseases, such as atherosclerosis, thromboembolic disorders and stroke, in addition to surgical procedures such as restenosis, all share the plasminogen activator system as a central component in the pathogenesis of vascular injury. Since the development of plasminogen deficient mice our knowledge of the effects of this proteolytic system in cardiovascular disease has vastly increased. The plasminogen activator system plays a key role in vascular homeostasis and constitutes a critical… CONTINUE READING

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Diversity and functional evolution of the plasminogen activator system.

  • Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  • 2018
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