Plasminogen activator inhibitor activity as a possible indicator of disease activity in rest angina with angiographically insignificant coronary artery stenosis.

@article{Sakata1991PlasminogenAI,
  title={Plasminogen activator inhibitor activity as a possible indicator of disease activity in rest angina with angiographically insignificant coronary artery stenosis.},
  author={Konomi Sakata and Chinori Kurata and Atsushi Kobayashi and Andrzej Rydzewski and Noriko Yamazaki},
  journal={Thrombosis research},
  year={1991},
  volume={63 5},
  pages={491-502}
}
To assess the role of fibrinolytic system, 19 patients with rest angina and insignificant coronary artery stenosis and 23 controls performed symptom-limited multistage exercise. Vasospasm was angiographically demonstrated in 12 patients. Pre- and peak exercise blood samples from each patient were assayed to determine the fibrinolytic components. The patients displayed significantly increased PAI activity both under the basal conditions (p less than 0.01) and at peak exercise (p less than 0.01… CONTINUE READING