Plasminogen activator inhibitor-1 induction after experimental intracerebral hemorrhage.

  title={Plasminogen activator inhibitor-1 induction after experimental intracerebral hemorrhage.},
  author={Y -J. Hua and Guohua Xi and Richard F. Keep and Jimin Wu and Yajun Jiang and Julian T. Hoff},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  volume={22 1},
Serine proteases, such as thrombin and tissue-type plasminogen activator, play an important role in brain injury after intracerebral hemorrhage and other neurologic disorders. Plasminogen activator inhibitor-1 is one of the serine protease inhibitors, or serpins. The balance between serine proteases and serpins may affect the outcome of intracerebral hemorrhage. The purpose of this study was to determine whether plasminogen activator inhibitor-1 and tissue-type plasminogen activator are… CONTINUE READING
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