Plasminogen activator inhibitor-1 and thrombotic cerebrovascular diseases.

Abstract

Alterations in thrombosis and fibrinolysis comprise important parts of stroke pathophysiology. A key step in the fibrinolytic process includes the tissue-type plasminogen activator (tPA)-mediated conversion of the proenzyme plasminogen into the active protease plasmin, which in turn degrades the fibrin structure of intravascular thrombi. There are a number… (More)

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Cite this paper

@article{TjrnlundWolf2012PlasminogenAI, title={Plasminogen activator inhibitor-1 and thrombotic cerebrovascular diseases.}, author={Anna Tj{\"a}rnlund-Wolf and Hel{\'e}n Brogren and Eng H. Lo and Xiaoying Wang}, journal={Stroke}, year={2012}, volume={43 10}, pages={2833-9} }