Plasminogen activator in early embryogenesis: enzyme production by trophoblast and parietal endoderm.

@article{Strickland1976PlasminogenAI,
  title={Plasminogen activator in early embryogenesis: enzyme production by trophoblast and parietal endoderm.},
  author={Sidney Strickland and E. -P. Reich and Michael I. Sherman},
  journal={Cell},
  year={1976},
  volume={9 2},
  pages={231-40}
}
We have surveyed the early stages in the development and differentiation of cultured mouse embryos for plasminogen activator production. This enzyme is first detectable by the sixth equivalent gestation day. Thereafter, cultured blastocysts produce plasminogen activator with a biphasic time course: in the first phase, enzyme secretion rises to a maximum at about the eighth day and then decreases; a second phase, during which more enzyme accumulates, begins somewhat later and continues to at… CONTINUE READING

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