Plasminogen activation by single-chain urokinase in functional isolation. A kinetic study.

@article{Ellis1987PlasminogenAB,
  title={Plasminogen activation by single-chain urokinase in functional isolation. A kinetic study.},
  author={Vincent Ellis and Michael F. Scully and Vijay Vir Kakkar},
  journal={The Journal of biological chemistry},
  year={1987},
  volume={262 31},
  pages={14998-5003}
}
The kinetics of the activation of Glu- and Lys-plasminogen by single-chain urokinase (sc urokinase) derived from the transformed human kidney cell line TCL-598 have been studied and compared with two-chain urokinase (tc urokinase). Plasminogen activation was determined by the increase in fluorescence polarization of fluorescein-labeled aprotinin, a high… CONTINUE READING