Plasminogen: purification from human plasma by affinity chromatography.

  title={Plasminogen: purification from human plasma by affinity chromatography.},
  author={Dale G. Deutsch and E T Mertz},
  volume={170 3962},
Plasminogen was prepared from human plasma by affinity chromatography on L-lysine-substituted Sepharose. Thirty milligrams of plasminogen, with a specific activity of 100 caseinolytic units (Committee on Thrombolytic Agents) per milligram of nitrogen, were obtained from 340 milliliters of plasma. This corresponds to over 200-fold purification from plasma. Disc-gel electrophoresis at pH 8.3 indicated seven distinct bands, all of which contained activity. 

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 338 extracted citations

Similar Papers

Loading similar papers…