Plasmin catalyzes binding of lipoprotein (a) to immobilized fibrinogen and fibrin.

@article{Harpel1989PlasminCB,
  title={Plasmin catalyzes binding of lipoprotein (a) to immobilized fibrinogen and fibrin.},
  author={Peter C. Harpel and Bruce R. Gordon and Thomas S. Parker},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1989},
  volume={86 10},
  pages={3847-51}
}
Lipoprotein (a) [Lp(a)] is a plasma component whose concentration is related to the development of atherosclerosis, although the underlying mechanisms are not known. Lp(a) contains a unique structure, apolipoprotein (a), that shares partial homology with plasminogen. We now report that plasmin catalyzes the binding of Lp(a) to both immobilized fibrinogen and fibrin in a manner analogous to our previously reported studies with plasminogen. Plasmin treatment of immobilized fibrinogen induces a 3… CONTINUE READING
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