Plasmids of the same Inc groups in Enterobacteria before and after the medical use of antibiotics

@article{Datta1983PlasmidsOT,
  title={Plasmids of the same Inc groups in Enterobacteria before and after the medical use of antibiotics},
  author={Naomi Datta and Victoria M. Hughes},
  journal={Nature},
  year={1983},
  volume={306},
  pages={616-617}
}
Conjugative plasmids were common in enterobacteria isolated before the medical use of antibiotics. Plasmid F of Escherichia coli K-12 was one example and we1 identified others in over 20% of a collection of strains isolated between 1917 and 1954, the Murray collection. In the past 25 years, conjugative plasmids encoding antibiotic resistances have become common in bacteria of the same genera as those of the Murray Collection—Salmonella, Shigella, Klebsiella, Proteus, Escherichia. The present… CONTINUE READING