Plasmids of the pT181 family show replication-specific initiator protein modification.

@article{Rasooly1994PlasmidsOT,
  title={Plasmids of the pT181 family show replication-specific initiator protein modification.},
  author={A Rasooly and Steven J. Projan and Richard P. Novick},
  journal={Journal of bacteriology},
  year={1994},
  volume={176 8},
  pages={2450-3}
}
The rolling circle plasmids of Staphylococcus aureus regulate their replication by controlling initiator (Rep) protein synthesis. It was demonstrated recently that the pT181 initiator protein RepC is inactivated during pT181 replication by the addition of an oligodeoxynucleotide, giving rise to a new form, RepC* (A. Rasooly and R. P. Novick, Science, 262:1048-1050). We establish here that this initiator modification occurs with four other members of the pT181 family and that it occurs in… CONTINUE READING

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