Plasmids in Gram negatives: molecular typing of resistance plasmids.

  title={Plasmids in Gram negatives: molecular typing of resistance plasmids.},
  author={Alessandra Carattoli},
  journal={International journal of medical microbiology : IJMM},
  volume={301 8},
A plasmid is defined as a double stranded, circular DNA molecule capable of autonomous replication. By definition, plasmids do not carry genes essential for the growth of host cells under non-stressed conditions but they have systems which guarantee their autonomous replication also controlling the copy number and ensuring stable inheritance during cell division. Most of the plasmids confer positively selectable phenotypes by the presence of antimicrobial resistance genes. Plasmids evolve as an… CONTINUE READING