Plasmid-mediated susceptibility to intestinal microbial antagonisms in Escherichia coli.

@article{Andremont1985PlasmidmediatedST,
  title={Plasmid-mediated susceptibility to intestinal microbial antagonisms in Escherichia coli.},
  author={Antoine Andremont and Guy Gerbaud and Cyrille Tancr{\`e}de and Patrice Courvalin},
  journal={Infection and immunity},
  year={1985},
  volume={49 3},
  pages={751-5}
}
Self-transferable plasmid pIP1100 confers to Escherichia coli an unusually high level of resistance (1 to 2 mg/ml) to erythromycin by production of an erythromycin esterase. The effect of pIP1100 on the destiny of E. coli strains in the intestines of gnotobiotic mice was studied. In germfree mice, pIP1100 was efficiently transferred to a plasmid-free E. coli recipient. Intestinal counts of the donor, the recipient, and the transconjugants were greater than 8.5 log CFU/g of feces. When… CONTINUE READING

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