Plasmapheresis in Raynaud's phenomenon in systemic sclerosis: a microcirculatory study.

@article{Jacobs1991PlasmapheresisIR,
  title={Plasmapheresis in Raynaud's phenomenon in systemic sclerosis: a microcirculatory study.},
  author={Michael J. H. M. Jacobs and Paul J G J{\"o}rning and E J van Rhede van der Kloot and Peter J.E.H.M. Kitslaar and H. A. J. Lemmens and D. W. Slaaf and Robert S. Reneman},
  journal={International journal of microcirculation, clinical and experimental},
  year={1991},
  volume={10 1},
  pages={
          1-11
        }
}
Microcirculatory and haemorheological parameters were investigated before and after plasmapheresis in eighteen patients with secondary Raynaud's phenomenon based on progressive systemic sclerosis. After 4 plasmaphereses, once a week, all patients claimed explicit improvement of their complaints. Raynaud's phenomenon and especially the reaction upon cold provocation had disappeared and skin ulcers healed. Red blood cell (RBC) velocity increased significantly (p less than 0.001) after 4 weeks… CONTINUE READING

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