Plasma von Willebrand Factor Antigen (vWF:AG) and thrombomodulin (TM) levels in Adult Thrombotic Thrombocytopenic Purpura/Hemolytic Uremic Syndromes (TTP/HUS) and bone marrow transplant-associated thrombotic microangiopathy (BMT-TM).

@article{Zeigler1996PlasmaVW,
  title={Plasma von Willebrand Factor Antigen (vWF:AG) and thrombomodulin (TM) levels in Adult Thrombotic Thrombocytopenic Purpura/Hemolytic Uremic Syndromes (TTP/HUS) and bone marrow transplant-associated thrombotic microangiopathy (BMT-TM).},
  author={Zella R Zeigler and Craig S. Rosenfeld and David F. Andrews and John Nemunaitis and Jane M. Raymond and Richard K. Shadduck and Robert E. Kramer and Jeffrey F Gryn and Peter Rintels and Emmanuel C. Besa and James N George},
  journal={American journal of hematology},
  year={1996},
  volume={53 4},
  pages={
          213-20
        }
}
Endothelial damage is thought to be a contributing factor in the pathogenesis of Thrombotic Thrombocytopenic Purpura/Hemolytic Uremic Syndromes (TTP/HUS). The present studies measured two markers of endothelial cell stimulation and/or activation [von Willebrand Factor (vWF:Ag) and thrombomodulin (TM)] in patients with TTP/HUS disorders and compared them to controls. The patient groups consisted of adults with TTP/HUS, with (n = 13) and without (n = 14) peak Cr levels >2.0 mg/dl. Additionally… CONTINUE READING
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