Plasma vascular endothelial growth factor, angiopoietin-1, and angiopoietin-2 in diabetes: implications for cardiovascular risk and effects of multifactorial intervention.

@article{Lim2004PlasmaVE,
  title={Plasma vascular endothelial growth factor, angiopoietin-1, and angiopoietin-2 in diabetes: implications for cardiovascular risk and effects of multifactorial intervention.},
  author={Hoong Sern Lim and Andrew D. Blann and Aun Yeong Chong and Bethan Freestone and Gregory Y. H. Lip},
  journal={Diabetes care},
  year={2004},
  volume={27 12},
  pages={2918-24}
}
OBJECTIVE Vascular endothelial growth factor (VEGF) and angiopoietin (Ang)-1 and Ang-2 are mediators of angiogenesis. More recent data suggest that the balance between these growth factors may affect vascular endothelial integrity. Because diabetes is closely associated with endothelial perturbation, we studied plasma levels of these angiogenic growth factors in patients with diabetes; their relationship with glycemia, inflammation, and endothelial damage/dysfunction; and the effect of… CONTINUE READING