Plasma terminal half-life.

  title={Plasma terminal half-life.},
  author={P. L. Toutain and Alain Bousquet-M{\'e}lou},
  journal={Journal of veterinary pharmacology and therapeutics},
  volume={27 6},
Terminal plasma half-life is the time required to divide the plasma concentration by two after reaching pseudo-equilibrium, and not the time required to eliminate half the administered dose. When the process of absorption is not a limiting factor, half-life is a hybrid parameter controlled by plasma clearance and extent of distribution. In contrast, when the process of absorption is a limiting factor, the terminal half-life reflects rate and extent of absorption and not the elimination process… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 56 extracted citations

Similar Papers

Loading similar papers…