Plasma storage at -80 degrees C does not protect matrix metalloproteinase-9 from degradation.

@article{Rouy2005PlasmaSA,
  title={Plasma storage at -80 degrees C does not protect matrix metalloproteinase-9 from degradation.},
  author={Didier Rouy and Isabelle Ernens and C{\'e}line Jeanty and Daniel R. Wagner},
  journal={Analytical biochemistry},
  year={2005},
  volume={338 2},
  pages={294-8}
}
Recently, matrix metalloproteinase-9 (MMP-9) has been identified as a cardiovascular risk marker and is increasingly being determined in clinical studies. Among other matrix metalloproteinases, MMP-9 is known to be self-activable, as the cleavage of the propeptide leads to the formation of an active enzyme. In such a case the issue of storage of biological samples such as plasmas is of outstanding importance, as an enzymatic activity, although minimal, may remain at common storage temperature… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 36 extracted citations

Effect of biobanking conditions on short-term stability of biomarkers in human serum and plasma.

Clinical chemistry and laboratory medicine • 2014
View 4 Excerpts
Highly Influenced

NIH Common Fund HuBMAP

2017
View 1 Excerpt

Similar Papers

Loading similar papers…