Plasma sCD36 is associated with markers of atherosclerosis, insulin resistance and fatty liver in a nondiabetic healthy population.

@article{Handberg2012PlasmaSI,
  title={Plasma sCD36 is associated with markers of atherosclerosis, insulin resistance and fatty liver in a nondiabetic healthy population.},
  author={A Handberg and Kurt H\ojlund and Amalia Gastaldelli and Allan Flyvbjerg and Jacqueline M. Dekker and John T Petrie and Piermarco Piatti and Henning Beck-Nielsen},
  journal={Journal of internal medicine},
  year={2012},
  volume={271 3},
  pages={294-304}
}
OBJECTIVES Insulin resistance is associated with increased CD36 expression in a number of tissues. Moreover, excess macrophage CD36 may initiate atherosclerotic lesions. The aim of this study was to determine whether plasma soluble CD36 (sCD36) was associated with insulin resistance, fatty liver and carotid atherosclerosis in nondiabetic subjects. METHODS In 1296 healthy subjects without diabetes or hypertension recruited from 19 centres in 14 European countries (RISC study), we determined… CONTINUE READING
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